Medical Articles 8/30

Posted by rob on August 28, 2007 under Uncategorized | Be the First to Comment

Rapid assessment of early biophysical changes in K562 cells during apoptosis determined using dielectrophoresis.

FTY720,
a new alternative for treating blast crisis chronic myelogenous
leukemia and Philadelphia chromosome-positive acute lymphocytic
leukemia.

Medical Articles 8/24

Posted by rob on August 25, 2007 under Uncategorized | Be the First to Comment

Association of Nucleophosmin negatively regulates CXCR4-mediated G protein activation and chemotaxis.

Nilotinib
(formerly AMN107), a highly selective Bcr-Abl tyrosine kinase
inhibitor, is effective in patients with Philadelphia
chromosome-positive chronic myelogenous leukemia in chronic phase
following imatinib resistance and intolerance.
Peripheral
blood hematopoietic stem cell mobilization and collection efficacy is
not an independent prognostic factor for autologous stem cell
transplantation.
Mesenchymal
stem cells from patients with chronic myeloid leukemia do not express
BCR-ABL and have absence of chimerism after allogeneic bone marrow
transplant.

Granulocytic sarcoma involving the uterus and right fallopian tube with negative endometrial biopsy.

Medical Articles 8/22

Posted by rob on August 23, 2007 under Uncategorized | Be the First to Comment

Safety
and tolerability of velafermin (CG53135-05) in patients receiving
high-dose chemotherapy and autologous peripheral blood stem cell
transplant.

Sequential ABL kinase inhibitor therapy selects for compound drug-resistant BCR-ABL mutations with altered oncogenic potency.
Treatment-Related
Myelodysplastic Syndrome and Acute Myelogenous Leukemia in Patients
Treated With Ibritumomab Tiuxetan Radioimmunotherapy.
Impact
of Incompatible Killer Cell Immunoglobulin-like Receptor and Its Ligand
on the Outcome of Haploidentical Bone Marrow Transplantation.
[Detection of FLT3 Gene Mutation in Hematologic Malignancies and Its Clinical Significance.]
Role of Formulation Composition in Folate Receptor-Targeted Liposomal Doxorubicin Delivery to Acute Myelogenous Leukemia Cells.
Therapy-related Acute Myelogenous Leukemia and Myelodysplastic Syndrome.
Comparison of FISH and Quantitative RT-PCR for the Diagnosis and Follow-Up of BCR-ABL-Positive Leukemias.

Granulocytic sarcoma manifested as a parametrial mass mimicking a haemorrhagic abscess: a case report with CT and MR findings.

Medical Articles 8/19

Posted by rob on August 19, 2007 under Uncategorized | Be the First to Comment

Elevated
lactate dehydrogenase is an adverse predictor of outcome in HLA-matched
sibling bone marrow transplant for acute myelogenous leukemia.

Mcl-1
as a buffer for proapoptotic Bcl-2 family members during trail-induced
apoptosis: A mechanistic basis for sorafenib (BAY 43-9006)-induced
trail sensitization.
Genomic profile of chronic myelogenous leukemia: Imbalances associated with disease progression.
The ARF tumor suppressor in acute leukemias: insights from mouse models of Bcr-Abl-induced acute lymphoblastic leukemia.
Lack of association of XRCC1 codon 399Gln polymorphism with chronic myelogenous leukemia.
[Superior mesenteric and portal vein thrombosis in a polycythemia vera patient with JAK2 mutation]
Targeting
the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin
module for acute myelogenous leukemia therapy: from bench to bedside.
Kit: molecule of interest for the diagnosis and treatment of mastocytosis and other neoplastic disorders.

Binase induces apoptosis of transformed myeloid cells and does not induce T-cell immune response.

Happy Birthday To My Mom

Posted by rob on August 10, 2007 under Uncategorized | Be the First to Comment

Today, August 10, is my mom’s birthday. I wanted to wish her a Happy Birthday and to share some of the photos from her Birthday Party with you.

Rob

 

Laquita's Birthday Cake

Laquita’s birthday cake.

 

Laquita's Birthday Party

Laquita opening presents at her birthday party.

 

Alexandra And Laquita At Birthday Party

Alexandra and Laquita at the birthday party.

Medical Articles 8/10

Posted by rob on under Uncategorized | Be the First to Comment

Quantitative monitoring by polymerase colony assay of known mutations resistant to ABL kinase inhibitors.

The Btk tyrosine kinase is a major target of the Bcr-Abl inhibitor dasatinib.
The criteria for bone marrow recovery post-myelosuppressive therapy for acute myelogenous leukemia: a quantitative study.

Establishment of baseline toxicity expectations with standard frontline chemotherapy in acute myelogenous leukemia.

Waterfall

Posted by rob on August 9, 2007 under Uncategorized | Be the First to Comment

Cascata del Pison
From Lord Casco

Tryon, NC

Posted by rob on August 5, 2007 under Uncategorized | Be the First to Comment

Esso
From Van Liles

Medical Articles 8/3

Posted by rob on August 3, 2007 under Uncategorized | Be the First to Comment

Applying the discovery of the Philadelphia chromosome.

Treatment for chronic myelogenous leukemia: the long road to imatinib.
Discovery of the Philadelphia chromosome: a personal perspective.
The legacy of the Philadelphia chromosome.
Heat
shock protein 90: A Potential Therapeutic Target in Leukemic Progenitor
and Stem Cells Harboring Mutant BCR-ABL Resistant to Kinase Inhibitors.
Sequential
Flavopiridol, Cytosine Arabinoside, and Mitoxantrone: A Phase II Trial
in Adults with Poor-Risk Acute Myelogenous Leukemia.
Myeloid sarcoma presenting as an isolated nodule in a patient with acute myelogenous leukemia.
Nuclear factor kappakappaB as a target for new drug development in myeloid malignancies.

Aprotinin-associated
hemolytic thrombotic microangiopathy in a patient with acute
myelogenous leukemia (AML) and systemic coagulopathy.

home top