F-18 FDG PET/CT Findings in a Case of Gastric Relapse of Acute Myeloblastic Leukemia.
Posted by rob on October 24, 2009 under Uncategorized | 
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F-18 FDG PET/CT Findings in a Case of Gastric Relapse of Acute Myeloblastic Leukemia.
Clin Nucl Med. 2009 Nov;34(11):788-90
Authors: Suga K, Kawakami Y, Hiyama A, Takeda K, Tanizawa Y, Matsunaga N
An isolated extramedullary relapse of acute myelogenous leukemia (AML) after autologous bone marrow transplantation is uncommon. We report the F-18-fluorodeoxyglucose positron emission tomography-computed tomography (F-18 FDG PET/CT) findings in a 50-year-old man with a gastric relapse of AML. This patient had obtained complete remission (CR) of AML in the lumbar bone marrow by autologous bone marrow transplantation and induction chemoradiotherapy 6 years ago, and CR of the meduallary relapse in the bilateral femoral diaphyses by radiotherapy 2 years ago. Regardless of absence of clinical evidence indicative of relapses of AML, FDG PET/CT scan showed the FDG-avid protrusive mass with the maximum standardized uptake of 6.9 in the gastric fundus, which was histologically diagnosed as a relapse by endoscopic biopsy. After radiotherapy to the stomach, the second FDG PET/CT scan showed the disappearance of this FDG-avid gastric mass, and CR of this lesion was endoscopically confirmed. This case indicates that FDG PET/CT scan may be useful for noninvasively detecting a gastric relapse of AML and for monitoring treatment effect.
PMID: 19851176 [PubMed - in process]