Hematology: dasatinib regimens for patients with chronic myeloid leukemia.
Posted by rob on February 5, 2010 under Uncategorized | 
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Hematology: dasatinib regimens for patients with chronic myeloid leukemia.
Nat Rev Clin Oncol. 2009 Dec;6(12):680-2
Authors: Guilhot F, Roy L
Although imatinib mesylate therapy has dramatically improved the prognosis of patients in the advanced phases of chronic myeloid leukemia, room for improvement remains. Tyrosine kinase inhibitors are undergoing evaluation as second-line therapy for patients with imatinib-resistant disease. Kantarjian et al. recently demonstrated that once-daily dasatinib 140 mg is well tolerated and achieves a high response rate.
PMID: 19942922 [PubMed - indexed for MEDLINE]