Posted by rob on February 27, 2010 under Uncategorized | 
Conclusions: These single-step, closed-tube assays specifically target mutations associated with resistance to dasatinib or nilotinib. Compared with standard genotyping, such biased genotyping improves the detection of resistance or alternative features via quantitative analysis of the absolute amount of resistance. (Source: Clinical Chemistry)
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Posted by rob on under Uncategorized |
Leukemia cutis in a patient with acute myelogenous leukemia: a case report and review of the literature.
Cutis. 2010 Jan;85(1):31-6
Authors: Aguilera SB, Zarraga M, Rosen L
Leukemia cutis is an infiltration of malignant neoplastic leukocytes or their precursors into the epidermis, dermis, or subcutis. These neoplastic cells are derived from abnormal leukocytes in the bone marrow where maturation aberrations occur. Acute myelogenous leukemia (AML) is the second most common cause of leukemia cutis and the most common leukemia among adults. In the elderly population, AML presents a challenge to the medical community because of the number of preexisting comorbid conditions and the safety profile of useful chemotherapeutic agents.
PMID: 20184209 [PubMed - in process]
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