Acquired growth hormone deficiency in a girl with chronic myelogenous leukemia treated with tyrosine kinase inhibitor therapy

Posted by rob on December 25, 2010 under Uncategorized | Comments are off for this article

We report a seven?year?old identical twin with CML who developed significant growth delay, as compared to her twin, during five years of TKI therapy. Detailed endocrine evaluation showed acquired growth hormone deficiency, a pathway potentially inhibited by TKIs. Pediatr Blood Cancer © 2010 Wiley?Liss, Inc. (Source: Pediatric Blood and Cancer)
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