[A case of myeloid sarcoma in the anterior mediastinum].
Posted by rob on March 13, 2011 under Uncategorized | 
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[A case of myeloid sarcoma in the anterior mediastinum].
Nihon Kokyuki Gakkai Zasshi. 2011 Jan;49(1):25-9
Authors: Yamamoto H, Sanda R, Ota A, Kato M, Takagi Y, Sugino Y
We report a case of myeloid sarcoma in the anterior mediastinum. The patient was a 33-year-old man with a chief complaint of right shoulder pain, right upper limb edema, and cough. Chest contrast-enhanced computed tomography (CT) revealed a partially enhanced anterior mediastinal tumor. A CT-guided biopsy was then performed, and a Hematoxylin-eosin (HE) stain revealed mitosis of tumor cells and other cells, including eosinophils. Immunohistochemical stains with myeloperoxidase, CD34, CD43, CD68 and c-Kit tests were positive for tumor cells. Due to a pathological diagnosis of myeloid sarcoma, he was treated with chemotherapy based on a diagnosis of acute myelogenous leukemia. After complete remission was obtained, the patient visited another hospital to receive an unrelated bone marrow transplantation. Although it rarely occurs as a mediastinal tumor, the prognosis of myeloid sarcoma is unfavorable, and thus should be taken into consideration as a differential diagnosis.
PMID: 21384678 [PubMed - in process]